Active pharmaceutical ingredients (APIs) are the cornerstone of pharmaceuticals, responsible for the therapeutic effects of medications. While traditional APIs are well-defined and standardized, there exists a diverse category known as atypical active pharmaceutical ingredients (AAPIs). These substances offer unique properties and functionalities that can significantly enhance drug formulations and therapeutic outcomes.
The liver plays a crucial role in metabolizing proteins and eliminating waste products from the body, including ammonia. Ammonia, a toxic byproduct of protein metabolism, is typically converted into urea in the liver—a process that allows for its safe excretion through urine. However, in cases of liver cirrhosis or hepatic encephalopathy, the liver's ability to process ammonia is compromised, leading to a dangerous accumulation.